ABSTRACT
Angiolipoma is a benign variant of lipoma that is rare in the breast and may be confused clinically, radiologically and pathologically with other benign as well as malignant tumors. Clinicians, radiologists and pathologists in particular should not forget the existence of an angiolipoma of the breast to avoid unnecessary reaspiration of the lesion considering the smears with only adipose tissue fragments as inadequate. We report two cases of angiolipoma who presented with solitary lumps in the breast and a clinical diagnosis of fibroadenoma was suggested in both the cases. Both were diagnosed as lipoma on cytology and on excisional biopsy, a histopathological diagnosis of angiolipoma was given.
ABSTRACT
Present study was undertaken with a view to assess the utility of AgNOR counts in differentiating cervical lesions. One hundred cases of cervical lesions including normal, chronic cervicitis, CIN (I, II, III) and carcinoma were taken up for study during the period December 1995 to November 1996. Three micron thick sections of paraffin were subjected to AgNOR staining as described by Crocker and Smith with a little modification of 0.01% safranin counterstain. Statistical counts of AgNORs were done. The mean AgNOR counts in cervical epithelium showed a progressive and statistically significant increase from normal to chronic cervicitis to CIN, I, II and III (P<0.001). Scores in carcinoma also exceeded that of CIN (P<0.05). This can prove to be a useful adjunct to routine histopathology to evaluate cervical lesions.
Subject(s)
Uterine Cervical Dysplasia/pathology , Cervix Uteri/pathology , Diagnosis, Differential , Female , Humans , Nucleolus Organizer Region/pathology , Silver , Staining and Labeling , Uterine Cervical Neoplasms/pathology , Uterine Cervicitis/pathologyABSTRACT
Silver nucleolar organizer regions (AgNORs) were studied in one hundred specimens of endobronchial brushings. Bronchial biopsies were also obtained from these one hundred cases and subjected to AgNOR staining. These included twenty histologically normal cases, ten cases of inflammatory pathology and seventy cases of pulmonary neoplasms. Fixed cytologic smears and three micron thick sections of paraffin embedded tissue were subjected to AgNOR staining. The mean AgNOR counts in bronchial tissue showed a progressive and statistically significant increase from normal, through inflammatory to neoplastic lesions in both cytologic smears and histopathologic specimens. The AgNOR technique is simple, inexpensive and a useful adjunct to routine histopathology, to evaluate pulmonary lesions. The counts, however, cannot be standardized for a particular lesion as there are inter-laboratory variations.